PMID 37074394
The reta + cag combination covers more pathways on paper, but it has no trial data of its own
Wijdicks, MD, PhD, James Y
Intriguingly, when using the same probes ex vivo in Ussing chambers, the difference is much less pronounced with a LMR of ~0.8 ex vivo vs
The "gradual decline" group (approximately 40-50% of users) represents modal experience where benefits slowly regress toward pre-treatment baseline over 4-8 months, typically affecting users who completed shorter treatment courses (2-4 months), used lower concentrations or inconsistent application, possessed moderate to severe baseline skin damage requiring ongoing support, maintained adequate but not optimal complementary skincare, experienced significant lifestyle stressors affecting skin health including poor sleep or high stress, and faced genetic or age-related collagen production limitations
The Effectiveness of Aromatherapy in Reducing Pain: A Systematic Review and Meta-Analysis